Index of du Bois et al for Mortality in a Patient with Interstitial Lung Disease (ILD)

Description

du Bois et al developed an index for evaluating a patient with interstitial lung disease. This can help to identify a patient who may benefit from more aggressive management. The authors are from multiple institutions in Europe and the United States.

Patient selection: interstitial lung disease

Outcome: 1-year mortality

Parameters:

(1) age in years

(2) history of respiratory hospitalization

(3) FVC as percent of predicted

(4) 24-week change in FCV as percent of predicted

24-week change in FVC in percent of predicted =

= (current FVC as percent of predicted) - (FVC from 24 weeks ago as percent of predicted)

Parameter	Finding	Points
age in years	< 60 years	0
	60 to 69 years	4
	>= 70 years	8
history of respiratory hospitalization	no	0
	yes	14
FVC as percent of predicted	>= 80	0
	66 to 79	8
	51 to 65	13
	<= 50	18
24-week change in FVC	> -4.9	0
	-9.9 to -5	10
	<= -10	21

index =

= SUM(points for all 4 parameters)

Interpretation:

• minimum index: 0

• maximum index: 61

• The higher the index the greater the 1-year risk of death.

Index	1-Year Risk of Mortality
0 to 4	< 2%
8 to 14	2 to 5%
16 to 21	5 to 10%
22 to 29	10 to 20%
30 to 33	20 to 30%
34 to 37	30 to 40%
38 to 40	40 to 50%
41 to 43	50 to 60%
44 or 45	60 to 70%
47 to 49	70 to 80%
>= 50	> 80%

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Index of du Bois et al for Mortality in a Patient with Interstitial Lung Disease (ILD)

Description

Specialty