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Inaccurate Thyroglobulin Concentrations Associated with Thyroglobulin Autoantibodies

Specialty:

Clinical Laboratory
Immunology/Rheumatology
Endocrinology

Objective:

ICD-10:

Description:

For a patient with a history of thyroid cancer the concentration of thyroglobulin and its trend over time are useful for monitoring disease recurrence or progression. Autoantibodies to thyroglobulin can interfere with immune-based assays, resulting in false-positive or false-negative results.

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