Description

Xu et al developed a simple score based on findings seen during an intravascular ultrasound (IVUS) study performed after placement of a drug-eluting stent (DES). This can help to identify a patient who may benefit from more aggressive management. The authors are from Shenyang Northern Hospital in Shenyang, China.


 

Patient selection: following placement of a drug-eluting stent

 

Study: intravascular ultrasound (IVUS)

 

Parameters:

(1) i = inflow/outflow disease (significant residual disease in coronary segments outside of the treated segment, defined as > 70% plaque burden and a cross-sectional area < 4 square mm)

(2) M = malapposition (separation of at least one stent strut from the luminal border)

(3) U = underexpansion (inadequate stent expansion)

(4) T = tissure protrusion (visible tissue on the luminal side of stent struts)

(5) E = edge dissection (with 3 categories – intimal, medial and adventitial)

Parameter

Finding

Points

inflow/outflow disease

absent

0

 

present

1

malapposition

absent

0

 

present

1

underexpansion

absent

0

 

present

2

tissue protrusion

absent

0

 

present

1

edge dissection

absent

0

 

present

1

 

total score =

= SUM(points for all 5 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 6

• The higher the score the greater the risk of a major adverse cardiac event (MACE).

• A patient with an iMUTE score < 2 had a good chance of being free of a target vessel revascularization at 1 year (1.5% vs 7% if iMUTE >=2).

 


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