Implications of Dose and Response to Long-Term Granulocyte Colony Stimulating Factor (G-CSF) in a Patient with Severe Congenital Neutropenia


Rosenberg et al evaluated patients with severe congenital neutropenia who received long-term therapy with granulocyte colony stimulating factor (G-CSF). A patient who responds poorly to higher doses is at greater risk for a poor outcome. The authors are from the National Cancer Institute (NCI) and multiple institutions in the United States, Canada, Aurstralia and Europe.

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