Hung et al evaluated the impact of end-stage renal disease and cirrhotic complications on the survival of patients with cirrhosis. The authors are from Dalin Tzu Chi Hospital in Taiwan.
Patient selection: cirrhosis with end-stage renal disease
Major complications of cirrhosis (excluding hepatocellular carcinoma) include:
(1) ascites
(2) hepatic encephalopathy
(3) bleeding esophageal varices
Risk factors for mortality in the 3 years after a first hospitalization:
(1) older age
(2) male sex
(3) ascites
(4) hepatic encephalopathy
(5) bleeding esophageal varices
(6) hepatocellular carcinoma
(7) end-stage renal disease
For patients with cirrhosis and end-stage renal disease
Recent Complication
Past History of Complications
Median Survival in Days
absent
absent
620 days
absent
present
435 days
present
absent
200 days
present
present
265 days
from Figure 3
Recent Complication
Past History of Complications
3-Year Mortality
absent
absent
66.7%
absent
present
74.6%
present
absent
80.5%
present
present
83.5%
from Figure 2
In theory the presence of multiple complications would increase mortality.
To read more or access our algorithms and calculators, please log in or register.
