Overproduction of a monoclonal protein may be associated with underproduction of uninvolved immunoglobulins.
Immunoparesis is the suppression in the production of one or more uninvolved immunoglobulins associated with a monoclonal protein.
It may affect 1, 2 or more immunoglobulin isotypes.
It is a significant risk factor for progression to myeloma.
Number of Reduced Immunoglobulin Isotypes
Median Time to Progression
0
159 months
1
78 months
2
32 months
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Specialty: Hematology Oncology
