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Identification of Plasmodium falciparum Malaria Resistant to Sulfadoxine and Pyrimethamine Therapy Using Molecular Markers of DHFR and DHPS

Specialty:

Infectious Diseases
Clinical Pharmacology & Toxicology

Objective:

ICD-10:

Description:

Identification of mutations in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes of Plasmodium falciparum can predict resistance to sulfadoxine-pyrimethamine therapy. The original study was performed in Blantyre, Malawi.

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