High Molecular Weight Kininogen or Prekallikrein Deficiency Diagnosis

Are you evaluating a patient with a prolonged aPTT?

Yes

Does the patient have a bleeding disorder?

Yes

Do siblings or other close family members have an unexplained prolongation of the aPTT?

Yes

Is the PT normal?

Yes

Are levels of all the coagulation factors normal?

Yes

Does addition of normal plasma correct the aPTT?

Yes

Does exposure of plasma to glass correct the aPTT?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Number of findings suggesting a defect in the contact system

Is there evidence of a hereditary disorder?

Is there evidence for prekallikrein deficiency?

Should the plasma levels of prekallikrein be measured?

Should the plasma levels of high molecular weight kininogen be measured?

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Clinical Diagnosis, Including Family History For Genetics
- Clinical Findings in a Patient with an Hereditary Deficiency of Factor XII
- Clinical Findings in Patient with Hereditary Deficiency of Factor II (Prothrombin)
Laboratory Tests
Other Testing
- Correction of a Coagulation Factor Deficiency By Liver Transplantation
Criteria For Diagnosis
- Clinical Findings in a Patient with an Hereditary Deficiency of Factor XII
- Indications for Screening a Patient with Hemophilia A for a Factor VIII Inhibitor
Complications
- Indications for Screening a Patient with Hemophilia A for a Factor VIII Inhibitor
- Coagulation Factor Deficiency Following Liver Transplantation

Therapy

Options
- Perioperative Management of a Patient with Hereditary Deficiency of Factor XII
Selection
- Indications for Screening a Patient with Hemophilia A for a Factor VIII Inhibitor
- Correction of a Coagulation Factor Deficiency By Liver Transplantation
Administration

Monitoring

Response To Therapy
- Titer of VIII Inhibitor and Response to Factor VIII Replacement in Hemophilia A

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10

Identification of a Patient with a Hereditary Deficiency of Prekallikrein and/or High Molecular Weight Kininogen

Purpose: To evaluate a patient with a prolonged aPTT for evidence of a hereditary deficiency of prekallikrein and/or high molecular weight kininogen.

Evaluation

Results

Please fill out required fields.

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Power Your Solutions with 5,000+ Automated Medical Analytics

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10