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Identification of a Patient with a Hereditary Deficiency of Prekallikrein and/or High Molecular Weight Kininogen

Purpose:	To evaluate a patient with a prolonged aPTT for evidence of a hereditary deficiency of prekallikrein and/or high molecular weight kininogen.
Specialty:	Hematology Oncology Clinical Laboratory
Objective:	laboratory tests, criteria for diagnosis
ICD-10:	D68.8
Description:	Prekallikrein, high molecular weight kininogen and Factor XII are the contact factors involved in initiation of coagulation. Deficiencies of prekallikrein and/or high molecular weight kininogen are rare.

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Last website update January 22, 2020

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Identification of a Patient with a Hereditary Deficiency of Prekallikrein and/or High Molecular Weight Kininogen

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