
Identification of a Patient with a Hereditary Deficiency of Prekallikrein and/or High Molecular Weight Kininogen
Purpose: | To evaluate a patient with a prolonged aPTT for evidence of a hereditary deficiency of prekallikrein and/or high molecular weight kininogen. |
Specialty: | Hematology Oncology Clinical Laboratory |
Objective: | laboratory tests, criteria for diagnosis |
ICD-10: | D68.8 |
Description: | Prekallikrein, high molecular weight kininogen and Factor XII are the contact factors involved in initiation of coagulation. Deficiencies of prekallikrein and/or high molecular weight kininogen are rare. |
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