Hypertrophic Obstructive Cardiomyopathy Risk Factors for Sudden Death

Has the patient had a cardiac arrest associated with ventricular fibrillation?

Number of first degree relatives with sudden death when < 40 years of age secondary to HOC

Number of episodes of unexplained syncope within 1 year

Left ventricular wall thickness

Has the blood pressure increased > 25 mm Hg above baseline during strenuous exercise?

Has the blood pressure decreased by > 10 mm from the maximal blood pressure during exercise in an upright position?

Does the patient show left ventricular outflow obstruction?

Does the patient show perfusion defects on nuclear imaging or magnetic resonance imaging?

Does the patient have a high-risk mutation in the genes encoding the sarcoplasmic proteins?

Ventricular tachycardia