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Hypersensitivity Reaction to Drugs Formulated with Cremophor EL (Polyethoxylated Castor Oil)

Specialty:

Clinical Pharmacology & Toxicology
Emergency Medicine & Critical Care
Emergency Medicine & Critical Care
Immunology/Rheumatology

Objective:

ICD-10:

Description:

Several parenteral drugs are formulated with Cremophor EL (BASF), which is polyethoxylated castor oil. Some patients develop a pseudoallergic hypersensitivity reaction that can be life-threatening.

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