Hypergammaglobulinemia Differential Diagnosis | Medical Algorithm

Are you evaluating a patient with a marked elevation in serum gamma globulins?

Yes

Does the patient have?

• a chronic parasite infection (malaria, leishmaniasis, etc)?

Yes

• a chronic bacterial infection (endocarditis, osteomyelitis, etc)?

Yes

• infection with HIV?

Yes

• chronic viral hepatitis?

Yes

• sarcoidosis?

Yes

• Sjogren’s disease?

Yes

• systemic lupus erythematosus (SLE)?

Yes

• chronic liver disease (primary biliary cirrhosis, autoimmune hepatitis, cirrhosis)?

Yes

• a lymphoproliferative disorder (Casteleman’s disease, myeloma, Waldenstrom’s, etc)?

Yes

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Data complete?

Evaluation appropriate?

Number of possible explanations for the increase in gamma globulins

Should you request serum protein electropheresis?

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Interpretation and Description

References

Next Steps in Evaluation

Complication Detection
- Criteria for Decreased Levels of Serum Immunoglobulin A (IgA Deficiency States)

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Monitoring

Specialty

Objective

ICD-10

Differential Diagnosis of Marked Hypergammaglobulinemia

Purpose: To consider possible explanations for a marked elevation in serum gamma globulins.

Evaluation

Results

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MedicalAlgorithms.com APIs

Power Your Solutions with 5,000+ Automated Medical Analytics

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Monitoring

Specialty

Objective

ICD-10