A number of tumors may secrete aldosterone, resulting in clinical hyperaldosteronism. These tumors feature an elevated blood aldosterone concentration that normalizes if the tumor is completely resected.
The most common lesions associated with hyperaldosteronism are:
(1) unilateral or bilateral adrenal cortical adenomas
(2) adrenal hyperplasia
Tumors that can produce aldosterone include:
(1) primary or metastatic adrenocortical carcinoma
