Infections with the human metapneumovirus (HMPV) may range from mild to severe. A number of factors may increase the likelihood that a patient may experience a severe infection.


Many clinical laboratories do not routinely test for HMPV, so the prevelance is often underestimated.


Risk factors for severe disease:

(1) extremes of age (infants or children; older adults > 65 years of age)

(2) immunocompromised status, including HIV disease and organ transplantation

(3) comorbid conditions (asthma, COPD, congenital heart disease, cancer)


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