The HUGE formula can be used to identify a patient at risk for chronic renal failure.The authors are from multiple institutions in Salamanca and Badajoz in Spain.
Parameters:
(1) hematocrit in percent (H)
(2) urea in mmol/L (U)
(3) gender (GE)
Parameter
Finding
Points
hematocrit
-0.264418 * (hematocrit)
urea
0.1181 * (urea)
gender
female
0
male
1.38396
value of X =
= SUM(points for all 3 parameters) + 2.505458
Interpretation:
• A score < 0 indicates that chronic renal failure is unlikely.
• A score > 0 indicates an increased risk for chronic renal failure.
• A diabetic patient with an elevated HUGE score is at increased risk for cardiovascular disease.
• The score is triggered by significant anemia and elevated urea. The score may not be terribly sensitive.
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