The response of a head and neck tumor following therapy can be classified on FDG-PET/CT scans using criteria reported from the Johns Hopkins University.
Patient selection: patient with head and neck cancer following chemoradiation therapy
Examination: 18Fluorodeoxyglucose (FDG) PET/CT
Sites for comparison: internal jugular vein (IJV) and liver
Comparison to IJV
Comparison to Liver
Category
less than
less than
1
greater than
less than
2
greater than, diffuse
greater than, diffuse
3
greater than
greater than, focal
4
greater than
greater than, focal, intense
5
Category
Significance
1
complete metabolic response
2
likely complete metabolic response
3
likely inflammatory change
4
likely residual tumor
5
consistent with residual tumor
The appearance of a new lesion not seen on a previous scan (presumably category 4 or 5) indicates progressive disease.
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