Pasquier et al evaluated patients with hypothermic cardiac arrest who treated with extracorporeal life support. They reported the HOPE (Hypothermia Outcome Prediction after Extracorporeal life support) score predict outcome for these patients. The authors are from multiple institutions in Europe.
Patient selection: hypothermic cardiac arrest after extracorporeal life support
Outcome: survival (84% had good neurological outcome)
Parameters:
(1) age in years
(2) sex
(3) asphyxia-related mechanism
(4) serum potassium in mmol/L
(5) CPR duration in minutes
(6) core body temperature in °C on admission
Parameter
Finding
Points
age in years
-0.0191 * (age)
sex
female
0
male
-1.55
asphyxia mechanism
no
0
yes
-1.95
serum potassium
-2.07*LOG2(potassium)
CPR duration
-0.573*LOG2(CPR)
temperature
(0.937 * (temp)) - (0.0247 * ((temp)^2))
where:
• LOG2(X) = LN(X)/LN(2) = 1.44269*LN(X)
value of X =
= SUM(points for the 6 parameters) + 2.44
probability of survival =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.90.
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