Gao et al reported a prognostic model for a patient with a diffuse large B-cell lymphoma (DLBCL) involving the gastrointestinal tract. This can help to identify a patient who may require more aggressive management. The authors are from Peking University Third Hospital and Pingdingshan First People's Hospital in China.
Patient selection: gastrointestinal large B-cell lymphoma
HLAMA is based on the first letter of the 5 parameters.
Parameters:
(1) hemoglobin in g/L
(2) age in years
(3) serum LDH in U/L
(4) serum albumin in g/L
(5) maximum intra-abdominal lesion diameter (MIALD) in cm
Parameter
Finding
Points
age in years
< 75 years
0
>= 75 years
1
hemoglobin
< 105 g/L
2
>= 105 g/L
0
serum LDH
< 300 U/L
0
>= 300 U/L
1
serum albumin
< 38 g/L
1
>= 38 g/L
0
MIALD
< 4 cm
0
>= 4 cm
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
Total Score
Risk Category
5-Year Survival
0
low
100%
1 to 3
intermediate
65%
>= 4
high
0%
The authors also developed a simpler score using hemoglobin, serum LDH and age, with point assignment the same as above.
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