Laher et al reported a score for evaluating an HIV patient in the hospital. This can help to identify a patient who may require more aggressive management. The authors are from the University of Witwatersrand and University of Pretoria in South Africa.
Patient selection: hospitalized HIV-positive patient
Parameters:
(1) non-adherent or not yet on anti-retroviral therapy (ART)
(2) Glasgow coma scale, from 3 to 15
(3) respiratory rate in breaths per minute
(4) oxygen saturation in percent
(5) white blood cell count in 10^9/L
(6) serum creatinine in µmol/L
(7) serum lactate in mmol/L
(8) serum albumin in g/L
Parameter |
Finding |
Points |
ART |
on and adherent |
0 |
|
neither |
1 |
Glasgow coma scale |
15 |
0 |
|
3 to 14 |
2 |
respiratory rate |
<= 20 breaths per minute |
0 |
|
> 20 breaths per minute |
1 |
oxygen saturation |
>= 90% |
0 |
|
< 90% |
1 |
white blood cell count |
>= 4 * 10^9/L |
0 |
|
< 4 * 10^9/L |
1 |
serum creatinine |
<= 120 µmol/L |
0 |
|
> 120 µmol/L |
1 |
serum lactate |
<= 2 mmol/L |
0 |
|
> 2 mmol/L |
2 |
serum albumin |
>= 35 g/L |
0 |
|
< 35 g/L |
1 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 10
Total Score |
Inpatient Mortality |
0 |
< 1.2% |
1 |
1.2% |
2 |
1.7% |
3 |
3.2% |
4 |
4.7% |
5 |
6.8% |
6 |
10.5% |
7 |
15% |
8 |
21.5% |
9 |
34.8% |
10 |
81% |
Performance:
• The area under the ROC curve is 0.83.
Specialty: Infectious Diseases