Description

Laher et al reported a score for evaluating an HIV patient in the hospital. This can help to identify a patient who may require more aggressive management. The authors are from the University of Witwatersrand and University of Pretoria in South Africa.


Patient selection: hospitalized HIV-positive patient

 

Parameters:

(1) non-adherent or not yet on anti-retroviral therapy (ART)

(2) Glasgow coma scale, from 3 to 15

(3) respiratory rate in breaths per minute

(4) oxygen saturation in percent

(5) white blood cell count in 10^9/L

(6) serum creatinine in µmol/L

(7) serum lactate in mmol/L

(8) serum albumin in g/L

 

Parameter

Finding

Points

ART

on and adherent

0

 

neither

1

Glasgow coma scale

15

0

 

3 to 14

2

respiratory rate

<= 20 breaths per minute

0

 

> 20 breaths per minute

1

oxygen saturation

>= 90%

0

 

< 90%

1

white blood cell count

>= 4 * 10^9/L

0

 

< 4 * 10^9/L

1

serum creatinine

<= 120 µmol/L

0

 

> 120 µmol/L

1

serum lactate

<= 2 mmol/L

0

 

> 2 mmol/L

2

serum albumin

>= 35 g/L

0

 

< 35 g/L

1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 10

 

Total Score

Inpatient Mortality

0

< 1.2%

1

1.2%

2

1.7%

3

3.2%

4

4.7%

5

6.8%

6

10.5%

7

15%

8

21.5%

9

34.8%

10

81%

 

Performance:

• The area under the ROC curve is 0.83.


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