Movin et al developed a score to quantify histopathologic changes associated with tendinopathy. The authors are from Huddinge University Hospital in Sweden.
The tendon being examined should not be affected by rupture, acute trauma, or recent overuse.
Stains: routine hematoxylin and eosin (H&E); Alcian blue
Parameters:
(1) fiber structure
(2) fiber arrangement
(3) rounding of the nuclei
(4) regional variations in cellularity
(5) increased vascularity
(6) decreased collagen stainability
(7) hyalinization
(8) glycosaminoglycan (GAG) content on Alcian blue stained sections
Finding
Points
normal
0
slightly abnormal
1
moderately abnormal
2
markedly abnormal
3
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0 (normal)
• maximum score: 24
• The higher the score the more severe the histopathologic changes.
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