Description

The histopathologic changes seen in a patient with dry eye can be classified using the criteria of Marube et al. This is one of the three components of the triple classification defined at the 14th Congress of the Societas Ophthalmologica Europaea in June, 2003. The authors are from the University of Alcala in Madrid.


 

Acronym: ALMEN

 

Code

Histologic Factor

Diseased Component

A

aqueous glands

main and accessory lacrimal glands

L

lipid glands

Meibomian, Zeis, Moll glands

M

mucinous glands

goblet cells

E

epitheliopathy

corneal epithelium

N

nonocular exocrine deficiencies

other exocrine glands affected: nose, mouth, pharynx, larynx, skin, genital system, ear, GI tract

 

An affected component may be involved primarily or secondarily.

 


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