In general a sarcomatoid carcinoma consists of:
(1) a non-small cell lung carcinoma (NSCLC) component, often poorly differentiated
(2) sarcoma (rhabdo, osteo, chondro) or sarcomatoid (spindle cells, anaplastic giant cell) component
Subtypes:
(1) pleomorphic carcinoma
(2) spindle cell carcinoma
(3) giant cell carcinoma
(4) carcinosarcoma
(5) pulmonary blastoma
Pleomorphic carcinoma:
(1) >= 10% malignant spindle cells and/or anaplastic giant cells
(2) remainder (may be 0%) consists of a NSCLC (squamous, adeno, large cell, mixed)
Spindle cell carcinoma:
(1) carcinoma with all malignant spindle cells
Giant cell carcinoma:
(1) carcinoma with all anaplastic giant cells
Carcinosarcoma:
(1) component of NSCLC (squamous, adeno, large cell, mixed)
(2) sarcoma component (rhabdo, osteo, chondro, other)
Pulmonary blastoma - a biphasic tumor:
(1) primitive adenocarcinoma
(2) primitive mesenchymal stroma
(3) variable sarcoma component (rhabdo, osteo, chondro, other)
