A histologic section may show cracks or fissures for a number of reasons.
Appearance under the microscope: resemble cracks seen in the ground during a drought
Conditions that can cause tissue cracks:
(1) incomplete fixation
(2) problems during tissue processing (excessive dehydration, inadequate clearing, poor paraffin infiltration)
(3) water bath temperature too high
(4) excessive use of coolant spray during sectioning
To read more or access our algorithms and calculators, please log in or register.
Specialty: Clinical Laboratory
