Intraglandular proliferations:
(1) typical (benign prostatic hyperplasia or BPH)
(2) atypical (prostatic intraepithelial neoplasia or PIN)
(3) comedonecrosis (cancer)
Glandular proliferations:
(4) small gland (need to consider cancer vs look-alikes)
(5) large gland (need to consider cancer vs look-alikes)
(6) glomerulations = ball-like proliferation which may resemble a glomerulus (cancer)
Cellular infiltrations:
(7) sheet-like (need to primary cancer vs metastatic cancer)
(8) peri-neural (cancer)
(9) into fat (cancer)
Reactive processes:
(10) inflammation (prostatitis, be cautious diagnosing cancer)
(11) atrophy (be cautious diagnosing cancer; consider treated cancer)
(12) ischemic necrosis (vascular injury, BPH, cancer)
Spindle cell proliferation:
(13) stromal proliferation (BPH)
(14) fibrosis
(15) mucinous fibroplasias (suspicious for cancer)
