Riedel’s thyroiditis can be diagnosed if certain histopathologic features are present in the thyroid gland.
Histologic criteria for Riedel’s thyroiditis:
(1) There is inflammation of the thyroid gland that extends into adjacent tissues.
(2) Occlusive phlebitis should be present.
Exclusions - The following should be absent:
(1) granulomas and/or giant cells
(2) oncocytes (Hurthle cells)
(3) lymphoid follicles
(4) thyroid carcinoma
(1) plasma cells positive for IgA and/or IgG4
(2) antithyroid antibodies in the serum
(3) elevated IgG4 in the serum
(4) presence of normal thyroid tissue sharply demarcated from the inflammatory process
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Specialty: Endocrinology, Clinical Laboratory