Description

A number of herbal remedies may have unintentional adverse effects due to interactions with analgesic drugs.


 

Analgesic Drug

Herbal Remedy/Effect

Effect

NSAID (aspirin)

antiplatelet

bleeding

NSAID (aspirin)

coumarin

bleeding

aspirin

tamarind (Tamarindus indica)

bleeding

acetaminophen

salicylate containing (willow, meadowsweet)

nephrotoxicity

acetaminophen

Echinacea, kava

hepatotoxicity

opiate

sedative

increased sedation

opiate

ginseng

reduced analgesia

 

Herbs with antiplatelet effect:

(1) ginkgo (Ginkgo biloba L)

(2) garlic (Allium sativum)

(3) ginger (Gingiber officinale)

(4) bilberry (Vaccinium myrtillus)

(5) dong quai (Angelica sinensis)

(6) feverfew (Tanacetum parthenium)

(7) ginseng

(8) tumeric (Curcuma longa)

(9) meadowsweet (Filipendula ulmaria)

(10) willow (Salix sp)

 

Herbs with coumarin:

(1) chamomile (Matricaria recutita, Chamaemelum mobile)

(2) motherworth (Leonurs cardiaca)

(3) horse chestnut (Aesculus hipposcastanum)

(4) fenugreek (Trigonella foenum-graeum)

(5) red clover (Trifolium pratense)

 

Tamarind may increase bioavailability of aspirin, increasing its effect.

 


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