A woman with Wilson Disease may first present with a HELLP-like syndrome during pregnancy.

HELLP = hemolysis, elevated liver enzymes, low platelets


Features shared by HELLP and Wilson's disease:

(1) hemolytic anemia

(2) elevated liver enzymes

(3) low platelet count


Clues to diagnosis may include:

(1) family members with Wilson's disease

(2) neuropsychiatric findings

(3) Kayser-Fleischer rings

(4) cardiomyopathy

(5) unexplained arthritis

(6) postpartum acute liver failure

(7) evidence of hemolysis or liver disease prior to pregnancy

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