Heidelberg Pouchitis Activity Score (PAS) of Heuschen et al

stool frequency in 24 hours

< 8

0

8 - 10

2

11 - 13

4

>= 14

6

fecal urgency

absent

0

present

3

rectal bleeding

absent

0

present

3

edema on endoscopy

absent

0

present

1

granularity on endoscopy

absent

0

present

1

friability on endoscopy

absent

0

mild

1

severe

2

erythema on endoscopy

absent

0

mild

2

severe

3

mucosal flattening on endoscopy

absent

0

present

2

ulcerations/erosions on endoscopy

absent

0

mild

2

severe

3

PMN infiltrate on histology

absent

0

discrete and patchy (mostly confined to surface epithelium)

1

moderate, variable cryptitis and/or crypt abscesses

2

extensive with cryptitis and crypt abscesses

3

mononuclear cell infiltrate on histology

absent

0

mild and patchy

1

moderate

2

extensive

3

ulcerations/erosions on histology

absent

0

mild and superficial

1

moderate

2

extensive

3

villous atrophy on histology

absent

0

minimal

1

partial

2

subtotal to total

3