Cowger et al reported the HeartMateII Risk Score (HMRS) for evaluating patients having the HeartMate II left ventricular assist device (LVAD) implanted. The authors are from multiple institutions in the United States.
Patient select: HeartMate II LVAD
Outcome: 90-day mortality
Parameters:
(1) age in years
(2) serum albumin in g/dL
(3) serum creatinine in mg/dL
(4) INR
(5) center volume (number of LVAD placed at an institution during the study period, which was maximally 5 years)
Center Volume
Points
< 15
1
>= 15
0
HMRS =
= ((0.0274 * (age in years)) - (0.723 * (albumin)) + (0.74 * (creatinine)) + (1.136 * (INR)) + (0.807 * (points for center volume))
Interpretation:
• The higher the HMRS the worse the prognosis.
HMRS
Risk Group
90 Day Mortality
< 1.58
low
4% derivation, 8% validation
1.58 to 2.48
intermediate
16%
> 2.48
high
29%
Performance:
• The area under the ROC curve was 0.71.
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