Mehra et al reported a risk score patients with an implanted HeartMate3 left ventricular assist device (LVAD). The authors are from multiple institutions in the United States.
Patient selection: HeartMate 3 risk score
Outcome: mortality
Parameters:
(1) age in years
(2) history of prior CABG or valve procedure
(3) serum sodium in mmol/L
(4) serum BUN in mg/dL
(5) left ventricular end-diastolic diameter (LVEDD) in cm
(6) ratio of right atrial pressure (RAP) to pulmonary capillary wedge pressure (PCWP)
Parameter
Finding
Points
age in years
0.03496 * (age)
history of previous surgery
no
0
yes
0.53029
serum sodium
-0.04112 * ((sodium)-136)
serum BUN
0.01083 * (BUN)
LVEDD
< 5.5 cm
0.62149
>= 5.5 cm
0
ratio RAP/PCWP
<= 0.6
0
> 0.6
0.44785
total score =
= SUM(points for all of the parameters)
Total Score
Survival
2-Year Survival
< 2.41
higher
91%
2.41 to 2.96
average survival
83%
>= 2.97
lower
68%
Performance:
• The area under the ROC curve for 1-year outcomes was 0.75 and 0.70 for 2 years.
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