Heart block is described in neonates born to mothers with systemic lupus erythematosus (SLE). Rarely heart block can occur in an adult with SLE.

Patient selection: SLE


Clinical features:

(1) The patient presents with atrioventricular (AV) block, typically second degree or complete.

(2) The patient's serum is positive for autoantibodies, especially anti-Ro and/or anti-RNP.

(3) The heart block may improve after therapy with corticosteroids.

(4) Other causes of heart block are excluded.


Rarely the heart block may be the initial manifestation of SLE.

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