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Indications for HCV RNA Testing in HIV Patient Who is Negative for Anti-HCV Antibodies

Purpose:

To evaluate an HIV positive patient who is seronegative for HCV based on the findings of Chamie et al.

Specialty:

Infectious Diseases
Gastroenterology

Objective:

laboratory tests, differential diagnosis and mimics, red flags, comorbid conditions

ICD-10:

B17.1, B18.2, B20

Description:

Usually a patient is screened for infection with hepatitis C virus (HCV) based on the presence or absence of anti-HCV antibodies. Chamie et al identified HIV-positive patients who may be negative for these antibodies yet have HCV hepatitis. The authors are from the University of California in San Francisco, multiple hospitals in San Francisco and Oakland, the University of Iowa and Washington University in St.Louis.

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