Description

Meier et al developed the Hannover II scoring system for evaluating the findings from a sentinel lymph node biopsy performed on a patient with malignant melanoma. This can help to identify a patient who may benefit from a more aggressive or novel therapy. The authors are from the Hannover Medical School in Germany.


 

Parameters:

(1) maximum dimension of largest deposit in mm

(2) involvement of capsule (expansion of melanoma cells into the lymph node capsule)

(3) maximum tumor penetration depth in mm

 

Maximum Dimension

Involvement of Capsule

Maximum Tumor Penetration

Group

0 (negative)

NA

NA

1

< 0.1 mm

NA

NA

1

>= 0.1 mm

absent

<= 2 mm

2

>= 0.1 mm

present

<= 2 mm

2

>= 0.1 mm

absent

> 2 mm

2

>= 0.1 mm

present

> 2 mm

3

 

 

Group

Prognosis

Overall Survival at 8 Years (96 Months)

1

fair

80%

2

intermediate (guarded)

64%

3

poor

30%

 


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