Non-acute categories of change:
(1) chronic rejection (C)
(2) vasculopathy (B)
(3) fibrosis (F)
(4) non-rejection changes
|
Category
|
Features
|
Designation
|
|
chronic rejection
|
none
|
C-0
|
|
|
present
|
C-1
|
|
vasculopathy
|
none
|
B-0
|
|
|
slight (mild)
|
B-1
|
|
|
severe
|
B-2
|
|
fibrosis
|
none
|
F-0
|
|
|
present
|
F-1
|
|
non-rejection changes
|
none
|
E-0
|
|
|
present
|
E-1
|
Features of chronic rejection:
(1) interstitial and partly endocardial aggressive fibrosis
(2) persisting variable vasculopathy
Features of slight vasculopathy:
(1) endothelial swelling with degenerative changes
(2) slight perivascular mantle infiltrates
Features of severe vasculopathy:
(1) vascular necrosis
(2) massive intramural infiltrates
(3) endovasculopathy or thrombotic vasculopathy
Description of fibrosis may be by:
(1) localization
(1a) endocardial (e)
(1b) aggressive endocardial (ea)
(1c) interstitial (i)
(1d) aggressive interstitial (ia)
(2) percent distribution
