HALP and HALPG Scores of Guo et al for Predicting Prognosis for a Patient with Metastatic Prostate Cancer

Patient selection: male with metastatic prostate cancer undergoing cytoreductive radical prostatectomy

HALP is an acronym for hemoglobin, albumin, lymphocyte and platelet count

Parameters:

(1) hemoglobin in g/L

(2) serum albumin in g/L

(3) lymphocyte count in 10^9/L

(4) platelet count in 10^9/L

(5) Gleason score from 2 to 10

HALP score =

= (hemoglobin) * (albumin) * (lymphocyte count) / (platelet count)

Interpretation:

• A HALP score < 32.4 is considered low and a HALP score >= 32.4 is high.

• A score < 32.4 has a 2 year survival of 26% vs 72% for a score >= 32.4.

The HALPG index is a combination of the HALP score and Gleason score.

Performance:

• The area under the ROC curve is 0.74 for the HALPG score.