Description

Garcia et al have provided consensus guidelines for managing a patient with neurocysticercosis. The spectrum of therapy can range from none at all to aggressive drug therapy over a prolonged period to surgical resections.


 

Groups of neurocysticercosis:

(1) parenchymal (within the brain)

(2) extraparenchymal

(3) spinal

(4) ophthalmic

 

Types of parenchymal cysts:

(1) viable (live)

(2) degenerating (enhancing on CT)

(3) calcified (dead)

 

Infection Burden in Parenchymal Infection

Grade

1 – 5 cysts

mild

6 – 100 cysts

moderate

> 100 cysts

heavy

 

 

Parenchymal

Recommended Therapy

viable cysts, mild

antiparasitic therapy with steroids

viable cysts, ,moderate

antiparasitic therapy with steroids

viable cysts, heavy

antiparasitic therapy with high-dose steroids

degenerating cysts, mild to moderate

antiparasitic treatment; addition of steroids if side effects develop

degenerating cysts, heavy

no antiparasitic therapy; high dose steroids and osmotic diuretics

calcified (any number)

no antiparasitic therapy

 

 

Extraparenchymal

Recommended Therapy

ventricular

surgical removal if possible; ventricular shunt; antiparasitic therapy with steroids

subarachnoid

antiparasitic therapy with steroids, ventricular shunt if hydrocephalus

hydrocephalus without cysts

ventricular shunt; no antiparasitic therapy

 

where:

• Subarachnoid cysticercosis includes giant cysts, racemose cysticercosis and chronic meningitis.

• Basal subarachnoid cysticercosis has a poor prognosis and requires prolonged therapy.

Other Forms

Recommended Therapy

spinal cysticercosis (intra-or extra-medullary

surgical resection

ophthalmic cysticercosis

surgical resection

 


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