Varicella gangrenosa is a necrotizing fasciitis seen in patients with chickenpox. It is associated with a concurrent infection with Streptococcus pyogenes (Group A beta-hemolytic).
Clinical and laboratory features of varicella gangrenosa:
(1) The patient has evidence of an infection with Varicella-Zoster Virus (VZV).
(2) The patient develops a severe necrotizing fasciitis associated with:
(2a) fever
(2b) swelling and erythema in the affected area
(2c) severe pain
(2d) lethargy or irritability
(3) Culture of the lesions are positive for Streptococcus pyogenes.
Complications:
(1) sepsis
(2) disseminated intravascular coagulation (DIC)
(3) streptococcal toxic shock syndrome
(4) multi-organ failure
Survival of the patient may depend on early recognition and aggressive surgical management.
To read more or access our algorithms and calculators, please log in or register.
