In 1955 Truelove and Witts used a grading scheme for patients with ulcerative colitis during trials with cortisone therapy.
(1) number of bowel movements per day
(2) presence of macroscopic blood in stool
(4) heart rate
(6) erythrocyte sedimentation rate (ESR)
<= 4 per day
>= 6 per day
1-2 per day
blood in stool
none to small
normal (no fever)
mean evening temperature > 99.5°F (37.5°C) , OR a temperature >= 100°F (37.8°C) on at least 2 days out of 4
>= 90 per minutes
normal to mild anemia
<= 75% of normal, with allowance for recent transfusion
normal or returning to normal
<= 30 mm/h
> 30 mm/h
• The method for the ESR is not given. However, since an ESR of > 30 mm/h is referred to as "much raised", I will assume that they are using the Wintrobe method.
• Moderate disease is intermediate between mild and severe.
Data from Tietz (1995)
Normal ESR (Wintrobe method)
<= 13 mm/h
<= 9 mm/h
<= 20 mm/h
Lower limit of normal for hemoglobin
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