Novotny et al developed a grading system for symptoms associated seen with hyperleukocytic leukemia. The authors are from Universitatsklinikum Essen, Germany.
Parameters:
(1) limitations on activities
(2) pulmonary symptoms
(3) neurologic symptoms
(4) fatigue
(5) other findings
|
Parameter |
Finding |
Grade |
|
limitations on activities |
none |
0 |
|
|
mild |
1 |
|
|
moderate |
2 |
|
|
severe |
3 |
|
pulmonary symptoms |
none during normal activities |
0 |
|
|
mild during normal activities, comfortable at rest |
1 |
|
|
moderate during activities, with limitation in activities |
2 |
|
|
dyspnea at rest; requires oxygen or ventilatory support |
3 |
|
neurologic symptoms |
none |
0 |
|
|
mild tinnitus, headache and/or dizziness |
1 |
|
|
mild visual disturbances; severe tinnitus, headache and/or dizziness |
2 |
|
|
severe visual disturbances; confusion, delirium, somnolence, intracranial hemorrhage |
3 |
|
fatigue |
none or mild |
0 |
|
|
moderate |
1 |
|
|
severe |
2 |
|
other symptoms |
none |
0 |
|
|
myocardial infarction, ischemic necrosis and/or priapism |
3 |
where:
• Visual disturbances include blurred vision, diplopia and/or hemianopia.
The higher the grade the more severe the symptoms and the more likely that a patient with leukemia has the leukostasis syndrome.
Purpose: To grade symptoms in a patient with hyperleukocytic leukemia using the classification of Novotny et al.
Specialty: Hematology Oncology
Objective: clinical diagnosis, including family history for genetics, severity, prognosis, stage
ICD-10: C90, C91, C92, C93, C94, C95,
