GOUT-36 Prediction Rule for Gout Flare for an Inpatient

Description

Jatuworapruk et al reported the GOUT-36 prediction rule for identifying an inpatient with comorbid gout who will experience a flare of the condition. This can help to identify a patient who may benefit from preventive actions. The authors are from University of Otago, Thammasat University, University of Auckland, Naresuan University and Peking University International Hospital.

Patient: hospital inpatient with comorbid gout

Parameters:

(1) gout flare prophylaxis (colchicine, NSAIDS, oral corticosteroids) prior to admission

(2) urate-lowering therapy (allopurinol, febuxostat, probenecid, benzbromarone, sulfinpyrazonoe) prior to admission

(3) serum urate in the year prior to admission in mmol/L

(4) tophus

Parameter	Findings	Points
gout flare prophylaxis	no	1
	yes	0
urate-lowering therapy	no	1
	yes	0
serum urate	<= 0.36 mmol/L	0
	> 0.36 mmol/L	1
tophus	absent	0
	present	1

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 4

• A score >=2 indicates high risk for a flare, with sensitivity of 0.75 and specificity of 0.67.

Score	Risk
0	low
1	moderate
2	high
3 or 4	very high

Performance:

• The area under the ROC curve is 0.71.

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GOUT-36 Prediction Rule for Gout Flare for an Inpatient

Description

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