Parameters:
(1) gender
(2) age in years
(3) insulin-like growth factor-I (IGF-I) in ng/mL
(4) type III procollagen (P-III-P) in U/mL
score for a male =
= (2.905 * LN(P-III-P)) + (2.1 * LN(IGF-I)) - (101.737 / (age)) - 6.586
score for a female =
= (2.454 * LN(P-III-P)) + (2.195 * LN(IGF-I)) - (73.666 / (age)) - 8.459
Interpretation:
• A preliminary cutoff is 3.7, with a score > 3.7 indicating recent GH use.
The assay for measuring IGF-I was discontinued. It is necessary to convert values determined by other assays to approximate the value from this assay. A similar conversion is used if an alternative assay for P-III-P is used.
adjusted GH2000 IGF-I concentration in ng/mL =
= (0.66 * (DSL IGF-1 assay value)) =
= (11.37 * (Italan Mediagnost IGF-I)) - 6.07
adjusted GH2000 P-III-P in U/mL =
= (0.1 * (Italan Orion P-III-P value in ng/mL))