The GELTAMO International Prognostic Index (IPI) stratifies patients with diffuse large B-cell lymphoma (DLBCL) by prognosis. This can help to identify a patient who may benefit from more aggressive management. GELTAMO stands for the Grupo Espanol de Linfomas/Trasplante de Medula osea.
Patient selection: diffuse large-B cell lymphoma
Parameters:
(1) age in years
(2) Ann Arbor stage
(3) serum LDH relative to the upper limit of normal (ULN)
(4) serum beta-2 microglobulin relative to the upper limit of normal (ULN)
(5) ECOG performance status
Parameter
Finding
Points
age in years
< 65 years
0
65 to 79 years
1
>= 80 years
2
Ann Arbor Stage
I or II
0
III or IV
1
serum LDH
<= ULN
0
> ULN
1
serum beta-2 microglobulin
<= ULN
0
> ULN
1
ECOG performance status
0 or 1
0
2
1
3 or 4
2
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
• The higher the score the worse the prognosis.
Total Score
Risk Group
5-Year Overall Survival
0
low
93%
1 to 3
low-intermediate
79%
4
high-intermediate
66%
5 to 7
high
39%
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