Sometimes a patient with Gaucher's Disease will develop masses composed of Gaucher cells. Such a lesion is called a Gaucheroma.
The Gaucheroma is a slow-growing mass formed of Gaucher cells and histiocytes.
Gaucheromas are usually solitary but can be multiple.
Gaucheromas can occur:
(1) in the liver
(2) in the spleen
(3) in soft tissue
(4) in bone
(5) in lymph nodes
(6) within the abdomen
The masses appear hypodense on imaging studies. Histiocytes can accumulate iron, which can be expressed as R2*.
The differential diagnosis includes a cancer. The risk of cancer is increased in patients with Gaucher's disease.
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