Garcin Syndrome is a rare neurological disorder affecting multiple cranial nerves on one side.

Alternative: Guillain-Alajouanine-Garcin Syndrome


Clinical features:

(1) unilateral palsies of almost all cranial nerves (from I to XII)

(2) absence of sensory or motor long-tract disturbances

(3) absence of intracranial hypertension


Causes may include:

(1) primary tumor of the skull base (neurolymphoma, rhabdomyosarcoma, nasopharyngeal, osteosarcoma, myeloma, etc)

(2) metastatic carcinoma (breast, prostate, lung, colon, other) to the base of the skull

(3) rhinocerebralmucormycosis

(4) carotid aneurysm

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