Description

Garcin Syndrome is a rare neurological disorder affecting multiple cranial nerves on one side.


Alternative: Guillain-Alajouanine-Garcin Syndrome

 

Clinical features:

(1) unilateral palsies of almost all cranial nerves (from I to XII)

(2) absence of sensory or motor long-tract disturbances

(3) absence of intracranial hypertension

 

Causes may include:

(1) primary tumor of the skull base (neurolymphoma, rhabdomyosarcoma, nasopharyngeal, osteosarcoma, myeloma, etc)

(2) metastatic carcinoma (breast, prostate, lung, colon, other) to the base of the skull

(3) rhinocerebralmucormycosis

(4) carotid aneurysm


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