Description

Fulminant hepatitis with acute liver failure can rarely occur in patients with dengue fever although biochemical evidence of hepatitis is relatively common. The prognosis is usually poor.


Clinical features:

(1) young age (<= 40 years)

(2) jaundice

(3) severe bleeding

(4) exclusion of other causes of fulminant hepatitis

 

Laboratory findings:

(1) ALT and AST > 10 times the upper limit of normal

(2) thrombocytopenia

 

Additional risk factors may include:

(1) alcohol abuse


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