Fuchs Uveitis Syndrome (Fuchs Heterochromic Uveitis) causes a subset of uveitis. It may be associated with a broad range of infections and other conditions.
In most cases the findings are unilateral but they may be bilateral.
The patient may be asymptomatic or complain of:
(1) decreased vision
(2) blurred vision
(3) floaters
(4) irritation
Findings on exam:
(1) chronic, low-grade anterior uveitis
(2) uniformly distributed stellate keratic precipitates (KP) in the corneal epithelium
(3) other keratic precipitates (fine, mutton-fat, etc)
(4) cells in the anterior chamber
(5) stromal atrophy of the iris with variable heterochromia
(6) iris nodules (Koeppe nodules on the inner margin of the iris, other)
(7) iris vascular abnormalities
(8) vitreous opacities
(9) absence of posterior synechiae and cystoid macular edema
The diagnosis requires exclusion of alternative diagnoses. An alternative diagnosis should be looked for more diligently when findings are bilateral and features are atypical.
