Lagerqvist et al developed a score for evaluating adults with unstable coronary artery disease. This can help to identify a patient who may benefit from an early invasive treatment strategy. The authors participated in the FRIC II study (fast revascularizaton in instability in coronary disease).
Outcome: death or myocardial infarction at 1 year
Parameters:
(1) age in years
(2) gender
(3) diabetes mellitus
(4) history of a previous myocardial infarction (MI)
(5) ST segment depression
(6) serum troponin concentration
(7) blood marker of inflammation (interleukin-6 or C-reactive protein, with C-reactive protein more readily available)
|
Parameter |
Finding |
Points |
|
age in years |
< 70 years of age |
0 |
|
|
>= 70 years of age |
1 |
|
gender |
female |
0 |
|
|
male |
1 |
|
diabetes mellitus |
absent |
0 |
|
|
present |
1 |
|
history of previous MI |
absent |
0 |
|
|
present |
1 |
|
ST segment depression |
absent |
0 |
|
|
present |
1 |
|
serum troponin concentration |
normal |
0 |
|
|
elevated (>= 0.03 µg/L) |
1 |
|
marker of inflammation |
normal |
0 |
|
|
elevated (CRP >= 10 mg/L) |
1 |
FRISC score =
= SUM(points for the 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 7
• The higher the score the more likely that the patient will benefit from an early invasive treatment strategy.
|
Score |
Poor Outcome without Early Intervention |
Poor Outcome with Early Intervention |
|
0 to 2 |
7% (death 1.4%) |
8% (death 0.4%) |
|
3 or 4 |
16% (death 3.3%) |
11% (death 3%) |
|
5 to 7 |
37% (death 15%) |
17% (death 5%) |
Specialty: Cardiology
