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Free-to-Total PSA Ratio

Purpose:

To use the proportion of free to total PSA to identify patients with prostate cancer when the total PSA value shows a borderline or mild increase.

Specialty:

Urology
Clinical Laboratory

Objective:

laboratory tests

ICD-10:

N40, N41, C61

Description:

Frequently the significance of a given total prostate-specific antigen (PSA) level  may be unclear. PSA in the serum exists both complexed with alpha-1 antichymotrypsin and "free" (uncomplexed). The proportion of free PSA can help indicate the chance of prostate cancer in a patient.

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