Patient selection: >= 65 years of age in Japan
Parameters:
(1) fatigue (F): feel that everything done is an effort without a reason in the past 2 weeks
(2) resistance (R): climbing stairs without using the handrail or wall for support
(3) ambulation (A): difficulty walking 1 km without resting and without walking aids by self
(4) illness (I): hypertension, diabetes, cancer (excluding minor skin cancer), chronic lung disease, heart attack, congestive heart failure, angina, asthma, arthritis, stroke, kidney disease
(5) loss of weight (L): unintentional weight loss > 2-3 kg in the past 6 months
|
Parameters
|
Finding
|
Points
|
|
fatigue
|
yes
|
1
|
|
resistance
|
no
|
0
|
|
|
yes
|
1
|
|
ambulation
|
no
|
0
|
|
|
yes
|
1
|
|
illness
|
0 to 4
|
0
|
|
|
5 to 11
|
1
|
|
unintentional weight loss
|
no
|
0
|
|
|
yes
|
1
|
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• A cutoff of >= 2 can be used to identify a patient who may be frail.
• An additional evaluation is needed to make the diagnosis since the PPV is low (13%).
Performance:
• The area under the ROC curve is 0.86.
• The negative predictive value is 99.7% so is good for exclusion.
