Description

The formulation of a drug consists of all its components, both active and inactive.


Factors affecting the formulation:

(1) route of administration (oral, intravenous, intramuscular, transdermal, etc)

(2) liquid vs dry

 

The elements of a drug formulation may include:

(1) the drug compound

(2) preservatives

(3) stabilizers and buffers

(4) release and absorption modifiers (rapid vs slow vs time-released)

(5) distribution modifiers (liposomes for an intravenous drug)

(6) metabolism modifiers (usually an inhibitor)

(7) fillers or dilutions


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