Yu et al reported an equation for predicting lymph node metastases in a patient with prostate cancer. The authors are from Yale University and the Department fo Veterans Affairs Connecticut Healthcare System.
Patient selection: serum PSA < 26 ng/mL
Parameters:
(1) Gleason score
(2) serum PSA in ng/mL
(3) clinical T stage (cT1c, cT2a, cT2b, cT2c)
Parameter
Finding
Points
Gleason score
(score) - 5
serum PSA
0.333 * (PSA)
clinical T stage
cT1c
0
cT2a
1.5
cT2b, cT2c
3.0
percent with lymph node metastases =
= (points for Gleason score) * ((points for PSA) + (points for T stage))
Interpretation:
• A result > 15% indicates high-risk disease.
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